Cover of: Adriamycin | International Symposium on Adriamycin (1983 Hakone-machi, Japan)


its expanding role in cancer treatment : proceedings of the International Symposium on Adriamycin, July 14-16, 1983 Hakone, Japan
  • 508 Pages
  • 3.67 MB
  • English
Excerpta Medica , Amsterdam, Princeton
Doxorubicin -- Congresses., Cancer -- Chemotherapy -- Congre
Statementeditors, Makoto Ogawa, Franco M. Muggia, Marcel Rozencweig.
SeriesInternational congress series ;, no. 629
ContributionsOgawa, M., Muggia, Franco M., Rozencweig, Marcel.
LC ClassificationsRC271.A37 I57 1984
The Physical Object
Paginationxx, 508 p. :
ID Numbers
Open LibraryOL2968184M
ISBN 104900392227
LC Control Number84214278

Doxorubicin was excreted in the milk of one lactating patient, with peak milk concentration at 24 hours after treatment being approxi­ er therapy with 70 mg/m.

of doxorubicin given as a minute intravenous infusion and mg/m. of cisplatin as a hour intravenous infusion. ADRIAMYCIN Injection is a red coloured, clear solution and should be stored at 2°C - 8°C.

ADRIAMYCIN Injection is available in vials containing the active ingredient doxorubicin hydrochloride 10 mL, 20 mL, 50 mg/10 mL and mg/25 mg/5 mg/ mL. The inactive ingredient is % saline Size: 98KB. Women treated with Adriamycin (doxorubicin (conventional)) may go through menopause at a younger age than normal.

Talk with your doctor. This medicine may cause harm to the unborn baby if you take it while you are pregnant. Women must use birth control while taking Adriamycin (doxorubicin (conventional)) and for some time after the last Adriamycin book. Doxorubicin hydrochloride: Adriamycin book or with other modalities in the treatment of various solid tumors, including Breast, Ovarian, Bladder, Bronchogenic carcinoma, Malignant lymphomas and leukemias.

Doxorubicin, liposomal: AIDS-related Kaposi's sarcoma (KS) in patients who cannot tolerate or fail conventional therapy. Ovarian carcinoma. Adriamycin side effects. Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Some side effects may occur during the injection. Tell your caregiver right away if you feel dizzy, nauseated, light-headed, sweaty, or have a headache, chest tightness, back pain, trouble breathing, or swelling in your face.

First isolated in the early s, doxorubicin (DOX) is among the most effective anticancer agents ever developed. DOX has been used mainly for the treatment of breast cancer, solid tumors in children, soft tissue sarcomas, and aggressive lymphomas. However, the use of DOX may have dose-dependent cardiotoxic effects that generate changes in myocardial structure, which can.

Overview: The role of doxorubicin in treatment of rhabdomyosarcoma (RMS) has been controversial for 30 years. Despite its known activity in RMS, because of its risk of cardiotoxicity, its use is not justified in low-risk patients who have an excellent chance of cure with vincristine, actinomycin with or without cyclophosphamide, and Adriamycin book tumor treatment.

For patients with intermediate and. Adriamycin; Descriptions. Doxorubicin injection is used together with other medicines to treat cancer of the Adriamycin book, lymph system, bladder, breast, stomach, lungs, ovaries, thyroid, nerves, kidneys, bones, and soft tissues, including muscles and tendons.

It may also be used to treat other kinds of cancer, as determined by your doctor. Doxorubicin is the generic name for the trade name drug, Adriamycin®, as well as, Rubex®. In some cases health care professionals may use the trade names Adriamycin® or Rubex® when referring to the generic drug name Doxorubicin.

Drug Type: Doxorubicin is an anti-cancer (“antineoplastic” or “cytotoxic”) chemotherapy drug. International Symposium on Adriamycin by International Symposium on Adriamycin, Milan, Carter, Stephen K., and a great selection of related books, art and collectibles available now at.

Doxorubicin is contraindicated in patients with severe persistent drug-induced myelosuppression. References. Johnson PJ, Dobbs N, Kalayci C, Aldous MC, Harper P, Metivier EM, Williams R "Clinical efficacy and toxicity of standard dose adriamycin in hyperbilirubinaemic patients with hepatocellular carcinoma: relation to liver tests and.

Adriamycin (doxorubicin) is a cancer medication that has been used successfully in the management of several different cancers such as acute lymphoblastic leukemia, acute myeloblastic leukemia, Wilm’s tumor, breast and ovarian carcinomas, and many other cancers.

It belongs to a class of medicines called anthracycline antibiotics. I had both the Adriamycin and Cytoxin and then it was followed with Taxol. I have to tell you that I had not one side effect from the A/C, but when they gave me the Neulasta the 1st and only time I took it, I though I would die.

The side effectcs were horrendous. How to use Adriamycin 2 Mg/Ml Intravenous Solution. Read the Patient Information Leaflet if available from your pharmacist before you start receiving doxorubicin and each time you get an infusion.

Doxorubicin, sold under the trade names Adriamycin among others, is a chemotherapy medication used to treat cancer.

Details Adriamycin FB2

This includes breast cancer, bladder cancer, Kaposi's sarcoma, lymphoma, and acute lymphocytic leukemia. It is often used together with other chemotherapy agents. Doxorubicin is given by injection into a vein. Common side effects include hair loss, bone marrow suppression. Doxorubicin is effective in controlling a wide variety of canine and feline tumors (Table ).

Lymphoma is especially sensitive to doxorubicin and the prog-nosis improves if the multiagent protocol includes doxorubicin. Mechanism of action. Doxorubicin is a cell cycle-nonspecific drug but is most active in the S phase.

The physical structure. Doxorubicin may lower your body's resistance, and there is a chance you might get the infection the immunization is meant to prevent.

In addition, other persons living in your household should not take oral polio vaccine, since there is a chance they could pass the polio virus on to you. The chemotherapy drug doxorubicin is used to treat many types of cancer, but some patients who receive the drug develop heart problems.

Using new insights into how doxorubicin damages the heart, researchers have identified an experimental drug that may help protect the heart.

Adriamycin® (doxorubicin) is a broadspectrum chemotherapy drug used to fight many forms of cancer and has been used for decades. Adriamycin® is an orange-red liquid, which is diluted and painlessly administered directly into a vein. The slow intravenous administration of Adriamycin® usually takes about 15 to 20 minutes.

Adriamycin caused tumors in rats at several different tissue sites and by several different routes of exposure. A single intravenous injection of Adriamycin caused mammary-gland tumors in female rats in sev-eral studies.

In rats of unspecified sex, single or repeated subcutane-ous injections of Adriamycin caused cancer of the mammary gland. Doxorubicin: Anticancer Antibiotics details the development of doxorubicin as a wide-spectrum antitumor antibiotic. The book begins by tracing the discovery and development of doxorubicin, highlighting factors such as (a) the involvement of organic chemistry at an early stage, which allowed the rapid identification of doxorubicin and ensured its prompt availability for the clinical.

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Doxorubicin may cause dangerous effects on your heart. Call your doctor at once if you feel very weak or tired, or have fast heartbeats, shortness of breath (even with mild exertion), or swelling in your ankles or feet.

SLIDESHOW Skin Cancer Symptoms, Types, Images See Slideshow. Adriamycin (doxorubicin, DXR) is a commonly used antineoplastic agent, but its use is limited due to a dose-dependent cardiotoxicity.

Cases of DXR-induced cardiomyopathy have been described even 20 years after completion of treatment (Iliskovic and Singal, ).

Doxorubicin is commonly used in multidrug protocols for lymphoma, injection-site and other soft tissue sarcomas, and feline mammary carcinomas. Doxorubicin is diluted in 30 to 50 mL % NaCl and administered at 1 mg/kg or 25 mg/m 2 intravenously over 20 to 60 minutes every 2 to 3 weeks.

Doxorubicin aglycone. UNII-XT6C35L. More Molecular Weight: g/mol. Dates: Modify. Create. Contents. 1 Structures Expand this section. 2 Names and Identifiers Expand this section.

3 Chemical and Physical Properties Expand this section. DESCRIPTION. Doxorubicin is a cytotoxic anthracycline antibiotic isolated from cultures of Streptomyces peucetius var. bicin consists of a naphthacenequinone nucleus linked through a glycosidic bond at ring atom 7 to an amino sugar, daunosamine.

Chemically, doxorubicin hydrochloride is (8S,10S)[(3- Amino-2,3,6-trideoxy-a-L-lyxo-hexopyranosyl)-oxy]glycoloyl. Brand Name: Adriamycin, Rubex, Caelyx Drug Class: Antineoplastic, Anthracycline Antibiotic Uses of Doxorubicin. Doxorubicin is an Anthracycline type of Cytotoxic, Chemotherapy drug indicated in the treatment of various types of Cancer.

It is used in the treatment of resection of Breast Cancer in Women with other medications like Cyclophosphamide. You can also use it in the treatment. Doxorubicin comes as a solution (liquid) or as a powder to be mixed with liquid to be injected intravenously (into a vein) by a doctor or nurse in a medical facility.

It is usually given once every 21 to 28 days. The length of treatment depends on the types of drugs you are taking, how well your body responds to them, and the type of cancer you. ADRIAMYCIN is known to be very powerful at lowering the number of white blood cells and platelets in your blood.

This means that you have an increased chance of getting an infection or bleeding. Warnings. Doxorubicin should be administered under the supervision of an experienced cancer chemotherapy physician; Cumulative dose-related cardiotoxicity may occur.

Potentially fatal congestive heart failure (CHF) may occur months to years after completion of risk of developing CHF increases with increasing total cumulative doses of doxorubicin in excess of mg/m².

Adriamycin PFS (doxorubicin hydrochloride) may give a reddish color to urine, tears, and sweat that may last up to several days. This is a normal side effect of Adriamycin PFS (doxorubicin hydrochloride) and should not be mistaken for blood in your urine.

Description Adriamycin FB2

Temporary hair loss may occur.Abstract. This paper shall be devoted to a discussion of the activity of adriamycin given as a single agent in a variety of solid tumors.

Although as other papers in this symposium shall emphasize, single agent therapy with adriamycin in many of the solid tumors is less desirable and less effective than a number of combination regimens currently under evaluation, it is obligatory in any.This patient-friendly article is about chemotherapy drug, Doxorubicin (Adriamycin) and Doxil widely used for a number of cancers including breast cancer, bladder cancer, multiple myeloma, Kaposi’s sarcoma, lymphoma and Acute Lymphocytic Leukemia; first approved by the FDA indoxorubicin is toxic to cancer cells, and is administered intravenously.